![]() Methods: We conducted a comprehensive search of various databases, including Medline ( via PubMed), Cochrane, Embase, Web of Science, Chinese National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, and Wanfang Database from their inception to November 16, 2022. In light of this, our study aims to examine the efficacy and safety of this treatment approach for patients with MCI. Objective: Prior research has shown mixed results regarding the effectiveness of combining donepezil and traditional Chinese medicine (TCM) to treat mild cognitive impairment (MCI). 3Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.2Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China. ![]() 1Basic Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.Si-jia Yu 1 †, Hui-ling Tang 1 †, Wei-hong Li 1, Chen-li Bin 2, Zhang Liu 1, Zhao-hui Tang 1 * and Jing-hong Liang 3 *
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